Lupus Nephritis Treatment in Burlingame, Daly City, and San Mateo County | Dr. Leena Joshi, MD
Last reviewed by Dr. Leena Joshi, MD on July 2026
Lupus nephritis is kidney inflammation caused by systemic lupus erythematosus, an autoimmune disease. Dr. Leena Joshi treats lupus nephritis through comprehensive evaluation, medication management including immunosuppressive therapy, blood pressure control, and regular monitoring of kidney function. Dr. Joshi works closely with rheumatologists and other specialists to coordinate care for patients in Burlingame, Daly City, and San Mateo County, helping to slow disease progression and preserve kidney health.
What is lupus nephritis?
Lupus nephritis occurs when lupus, an autoimmune disease, causes the immune system to attack the kidneys. In lupus, the body mistakenly makes antibodies that target its own tissues. When these antibodies and immune cells damage the tiny filters in the kidneys called glomeruli, inflammation develops and the kidneys may struggle to remove waste and extra fluid from the blood. This condition can range from mild to severe. Some people have only small amounts of protein in their urine, while others may develop serious kidney damage that affects their overall health. Early detection and treatment are important to help protect kidney function. Dr. Joshi evaluates and manages lupus nephritis for patients throughout San Mateo County, including those in Daly City and surrounding communities.
Signs and symptoms
- Foamy urine due to excess protein
- Swelling in the legs, ankles, feet, or around the eyes
- High blood pressure
- Dark or cola-colored urine
- Frequent urination, especially at night
- Weight gain from fluid retention
- Joint pain or fatigue related to lupus activity
How Dr. Joshi manages lupus nephritis
Dr. Joshi begins with a thorough evaluation that may include urine tests, blood work to check kidney function and lupus activity, and sometimes a kidney biopsy to determine the type and severity of lupus nephritis. Treatment plans are individualized based on biopsy results and disease activity. Dr. Joshi may prescribe immunosuppressive medications to reduce inflammation and protect the kidneys, along with medications to control blood pressure and reduce protein loss in the urine. Regular monitoring through lab work helps Dr. Joshi track how well treatment is working and adjust medications as needed. As a lupus nephritis doctor in San Mateo County, Dr. Joshi collaborates closely with rheumatologists to coordinate comprehensive care. Dr. Joshi also provides guidance on dietary modifications that may help manage symptoms and protect kidney function. The goal of treatment is to achieve remission, preserve kidney function, and improve quality of life for patients in San Mateo County and throughout the region.
When to see a nephrologist for lupus nephritis
- You have been diagnosed with lupus and notice changes in urination or swelling
- Your rheumatologist detects protein or blood in your urine
- You have been diagnosed with lupus nephritis and need specialized kidney care
- Your blood pressure is difficult to control
- You experience worsening fatigue or swelling despite lupus treatment
- Your primary care doctor or rheumatologist recommends nephrology consultation
Frequently asked questions
Can lupus nephritis be cured?
Lupus nephritis cannot be cured, but it can often be controlled with appropriate treatment. Dr. Joshi works to achieve remission, where kidney inflammation is minimized and function is preserved. Many patients respond well to immunosuppressive therapy and maintain stable kidney function with ongoing monitoring and medication adjustments.
How often will I need to see Dr. Joshi for lupus nephritis?
Visit frequency depends on disease severity and treatment response. Initially, Dr. Joshi may see patients monthly to monitor treatment effectiveness. Once lupus nephritis is stable, appointments may be every three to six months. Dr. Joshi determines the appropriate schedule based on individual needs and lab results.
What tests are used to monitor lupus nephritis?
Dr. Joshi typically orders urine tests to check for protein and blood cells, blood tests to measure kidney function and lupus activity markers, and blood pressure monitoring. These tests help Dr. Joshi assess whether treatment is working and whether medication adjustments are needed to protect kidney health.
Will I need dialysis if I have lupus nephritis?
Most patients with lupus nephritis do not progress to dialysis, especially with early treatment. Dr. Joshi focuses on aggressive management to prevent severe kidney damage. Your individual risk depends on the type of lupus nephritis, how quickly treatment begins, and how well the disease responds to therapy.
Can I have children if I have lupus nephritis?
Pregnancy is possible for many women with lupus nephritis, but it requires careful planning. Dr. Joshi works with your rheumatologist and obstetrician to optimize disease control before conception and adjust medications to those safe during pregnancy. Close monitoring throughout pregnancy helps manage risks to both mother and baby.
Does diet affect lupus nephritis?
Diet modifications may help manage lupus nephritis symptoms. Dr. Joshi may recommend limiting sodium to control blood pressure and swelling, moderating protein intake depending on kidney function, and staying well hydrated. Dr. Joshi provides personalized dietary guidance based on lab results and individual health needs.
Dr. Leena Joshi, MD offers comprehensive lupus nephritis care at two convenient locations: 1750 El Camino Real Suite 301 in Burlingame and 1800 Sullivan Avenue Suite 507 in Daly City. To schedule a consultation, call (650) 355-5551.
This page is for general education and is not a substitute for medical advice. Always consult your physician about your specific situation.
Medically reviewed by Leena Joshi, MD.